Zofran: Indications & Usage

Zofran (Ondansetron) is a 5-HT3 receptor antagonist indicated for the prevention of:

nausea and vomiting associated with highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2.
nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy.
nausea and vomiting associated with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.
postoperative nausea and/or vomiting. (1)